Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (Middle Region) Peptide
Quick Overview for Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (Middle Region) Peptide (ABIN5518230)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- YSDGQSETIL GGLGLGLGGG DCRVKIATKA NPWDGKSLKP DSVRSQLETS
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))
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Background
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The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.
Alias Symbols: AFAR, AKR7, AFAR1, AFB1-AR1
Protein Size: 167 -
Gene ID
- 8574
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NCBI Accession
- NM_003689, NP_003680
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UniProt
- O43488
Target
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