Alpha Centractin (ACTR1A) (Middle Region) Peptide
Quick Overview for Alpha Centractin (ACTR1A) (Middle Region) Peptide (ABIN5518285)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- DWNDMERIWQ YVYSKDQLQT FSEEHPVLLT EAPLNPRKNR ERAAEVFFET
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ACTR1A (Alpha Centractin (ACTR1A))
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Background
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This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.
Alias Symbols: ARP1, Arp1A, CTRN1
Protein Size: 167 -
Gene ID
- 10121
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NCBI Accession
- NM_005736, NP_005727
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UniProt
- P61163
Target
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