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Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide

ISCU Reactivity: Human Host: Synthetic WB
Catalog No. ABIN5518321
  • Target See all ISCU products
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Western Blotting (WB)
    Sequence
    SAPARLYHKK VVDHYENPRN VGSLDKTSKN VGTGLVGAPA CGDVMKLQIQ
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
    Synonyms
    nifun Peptide, zC191D15.3 Peptide, si:ch211-191d15.3 Peptide, 2310020H20Rik Peptide, HML Peptide, ISU2 Peptide, NIFU Peptide, NIFUN Peptide, hnifU Peptide, RGD1309562 Peptide, AA407971 Peptide, Nifu Peptide, Nifun Peptide, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Peptide, iron-sulfur cluster assembly enzyme Peptide, iron-sulfur cluster assembly enzyme a Peptide, LOC409130 Peptide, ISCU Peptide, iscua Peptide, Iscu Peptide
    Background
    Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: HML, ISU2, NIFU, NIFUN, hnifU, 2310020H20Rik

    Protein Size: 167
    Gene ID
    23479
    NCBI Accession
    NM_014301, NP_055116
    UniProt
    Q9H1K1
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