Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide
ISCU
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5518321
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100 μg
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Quick Overview for Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide (ABIN5518321)
Target
ISCU
(Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SAPARLYHKK VVDHYENPRN VGSLDKTSKN VGTGLVGAPA CGDVMKLQIQ
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
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Background
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Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HML, ISU2, NIFU, NIFUN, hnifU, 2310020H20Rik
Protein Size: 167 -
Gene ID
- 23479
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NCBI Accession
- NM_014301, NP_055116
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UniProt
- Q9H1K1
Target
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