Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide
CDKN1C
Reactivity: Human
Host: Synthetic
WB
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- Target See all CDKN1C products
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- SACRSLFGPV DHEELSRELQ ARLAELNAED QNRWDYDFQQ DMPLRGPGRL
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
- Background
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This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2,
Protein Size: 316 - Gene ID
- 1028
- NCBI Accession
- NM_000076, NP_000067
- UniProt
- P49918
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