V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Peptide
Quick Overview for V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Peptide (ABIN5624573)
Target
Source
Application
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Peptide Type
- Synthetic
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Supplier Product No.
- 000-001-e71
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Supplier
- Rockland
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Purpose
- AKT2 Control Peptide
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Characteristics
- AKT 2, AKT-2, PKB, PKB beta, PKBBETA PRKBB, Protein kinase Akt 2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, blocking peptide
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Purification
- Purity was determined to be greater than 98% by analysis by RP-HPLC and by reducing and non-reducing SDS-PAGE.
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Purity
- Greater than 98% by analysis by RP-HPLC and by reducing and non-reducing SDS-PAGE.
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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) peptide
AKT2 Host: Synthetic WB, CP Sodium azide
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Application Notes
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Application Note: AKT2 Control peptide has been tested in western blot and is suitable as a control for polyclonal or monoclonal Anti-AKT2 in immunological assays.
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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Concentration
- 1.0 mg/mL
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Buffer
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Buffer: None
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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Expiry Date
- 6 months
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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Background
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Synonyms: AKT 2, AKT-2, PKB, PKB beta, PKBBETA PRKBB, Protein kinase Akt 2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, blocking peptide
Background: AKT2 Control peptide is for use in control assays with Anti-AKT2 (p/n 200-501-E71). AKT2 Antibody detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis, (ii) promotion of proliferation.
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Gene ID
- 208
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UniProt
- P31751
Target
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