Paired-Like Homeobox 2b (PHOX2B) (C-Term) Peptide
PHOX2B
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5671337
Quick Overview for Paired-Like Homeobox 2b (PHOX2B) (C-Term) Peptide (ABIN5671337)
Target
PHOX2B
(Paired-Like Homeobox 2b (PHOX2B))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- RAAAAAAAAA KNGSSGKKSD SSRDDESKEA KSTDPDSTGG PGPNPNPTPS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PHX2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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Background
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The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.
Alias Symbols: PHOX2B,PMX2B,
Protein Size: 314 -
Gene ID
- 8929
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NCBI Accession
- NP_003915
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UniProt
- Q99453
Target
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