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Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (Middle Region) Peptide

AKR7A2 Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5671415
$160.46
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100 μg
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Quick Overview for Aflatoxin Beta1 Aldehyde Reductase (AKR7A2) (Middle Region) Peptide (ABIN5671415)

Target

AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

Origin

Human

Source

  • 3
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    Middle Region

    Sequence

    LGLGGGDCRV KIATKANPWD GKSLKPDSVR SQLETSLKRL QCPQVDLFYL

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- AKR7A2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    AKR7A2 (Aflatoxin Beta1 Aldehyde Reductase (AKR7A2))

    Background

    The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde.

    Alias Symbols: AFAR, AKR7, AFAR1, AFB1-AR1

    Protein Size: 331

    Gene ID

    8574

    NCBI Accession

    NM_003689, NP_003680

    UniProt

    Q8NHP1
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