V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide
Quick Overview for V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide (ABIN5671419)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- NQDHERLFEL ILMEEIRFPR TLSPEAKSLL AGLLKKDPKQ RLGGGPSDAK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- AKT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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Background
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This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Alias Symbols: PKBB, PRKBB, HIHGHH, PKBBETA, RAC-BETA
Protein Size: 438 -
Gene ID
- 208
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NCBI Accession
- NM_001626, NP_001617
Target
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