Ataxin 10 (ATXN10) (Middle Region) Peptide
Quick Overview for Ataxin 10 (ATXN10) (Middle Region) Peptide (ABIN5671459)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- TNIFSNCGCV RAEGDISNVA NGFKSHLIRL IGNLCYKNKD NQDKVNELDG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- ATXN10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Ataxin 10 (ATXN10)
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Background
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This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
Alias Symbols: E46L, SCA10, HUMEEP
Protein Size: 475 -
Gene ID
- 25814
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NCBI Accession
- NM_001167621, NP_001161093
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UniProt
- Q9UBB4
Target
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