Cathepsin D (CTSD) (Middle Region) Peptide
CTSD
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671482
Quick Overview for Cathepsin D (CTSD) (Middle Region) Peptide (ABIN5671482)
Target
Cathepsin D (CTSD)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- HHKYNSDKSS TYVKNGTSFD IHYGSGSLSG YLSQDTVSVP CQSASSASAL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CTSD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Cathepsin D (CTSD)
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Background
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This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Alias Symbols: CPSD, CLN10, HEL-S-130P
Protein Size: 412 -
Gene ID
- 1509
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NCBI Accession
- NM_001909, NP_001900
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UniProt
- P07339
Target
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