TP53RK Binding Protein (TPRKB) (N-Term) Peptide
TPRKB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TPRKB products
- TPRKB (TP53RK Binding Protein (TPRKB))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTHQLDLFPE CRVTLLLFKD VKNAGDLRRK AMEGTIDGSL INPTVIVDPF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TPRKB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TPRKB (TP53RK Binding Protein (TPRKB))
- Background
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Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
Alias Symbols: CGI-121
Protein Size: 214 - Gene ID
- 51002
- NCBI Accession
- NM_016058, NP_057142
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