Forkhead Box P2 (FOXP2) (N-Term) Peptide
FOXP2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671584
Quick Overview for Forkhead Box P2 (FOXP2) (N-Term) Peptide (ABIN5671584)
Target
FOXP2
(Forkhead Box P2 (FOXP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MQESATETIS NSSMNQNGMS TLSSQLDAGS RDGRSSGDTS SEVSTVELLH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- FOXP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FOXP2 (Forkhead Box P2 (FOXP2))
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Background
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This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
Alias Symbols: SPCH1, CAGH44, TNRC10
Protein Size: 432 -
Gene ID
- 93986
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NCBI Accession
- NM_001172766, NP_001166237
Target
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