Hexokinase 2 (HK2) (Middle Region) Peptide
HK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671619
Quick Overview for Hexokinase 2 (HK2) (Middle Region) Peptide (ABIN5671619)
Target
Hexokinase 2 (HK2)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GRMCINMEWG AFGDDGSLND IRTEFDQEID MGSLNPGKQL FEKMISGMYM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- HK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Hexokinase 2 (HK2)
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Background
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Alias Symbols: HKII, HXK2
Protein Size: 917 -
Gene ID
- 3099
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NCBI Accession
- NM_000189, NP_000180
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UniProt
- P52789
Target
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