HNF1 Homeobox A (HNF1A) (Middle Region) Peptide
HNF1A
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for HNF1 Homeobox A (HNF1A) (Middle Region) Peptide (ABIN5671625)
Target
HNF1A
(HNF1 Homeobox A (HNF1A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- REVAQQFTHA GQGGLIEEPT GDELPTKKGR RNRFKWGPAS QQILFQAYER
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- HNF1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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HNF1 Homeobox A (HNF1A) peptide
HNF1A Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Background
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The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
Protein Size: 524 -
Gene ID
- 6927
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NCBI Accession
- NM_000545, NP_000536
Target
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