RAB8A, Member RAS Oncogene Family (RAB8A) (Middle Region) Peptide
RAB8A
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RAB8A products
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VNDKRQVSKE RGEKLALDYG IKFMETSAKA NINVENAFFT LARDIKAKMD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- RAB8A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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RAB8A, Member RAS Oncogene Family (RAB8A) peptide
RAB8A Reactivity: Human, Cow, Dog Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
- Background
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The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
Alias Symbols: MEL, RAB8
Protein Size: 207 - Gene ID
- 4218
- NCBI Accession
- NM_005370, NP_005361
- UniProt
- P61006
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