Nibrin (NBN) (C-Term) Peptide
NBN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671740
$160.46
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100 μg
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Quick Overview for Nibrin (NBN) (C-Term) Peptide (ABIN5671740)
Target
Nibrin (NBN)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- DKLQDDSEML PKKLLLTEFR SLVIKNSTSR NPSGINDDYG QLKNFKKFKK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- NBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Nibrin (NBN)
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Background
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Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Alias Symbols: ATV, NBS, P95, NBS1, AT-V1, AT-V2
Protein Size: 754 -
Gene ID
- 4683
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NCBI Accession
- NM_001024688, NP_001019859
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UniProt
- O60934
Target
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