Tyrosine Kinase 2 (TYK2) (C-Term) Peptide
TYK2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671748
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Tyrosine Kinase 2 (TYK2) (C-Term) Peptide (ABIN5671748)
Target
TYK2
(Tyrosine Kinase 2 (TYK2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LAKAVPEGHE YYRVREDGDS PVFWYAPECL KEYKFYYASD VWSFGVTLYE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TYK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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Background
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.
Alias Symbols: JTK1, IMD35
Protein Size: 1187 -
Gene ID
- 7297
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NCBI Accession
- NM_003331, NP_003322
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UniProt
- P29597
Target
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