Translin (TSN) (Middle Region) Peptide
TSN
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672045
Quick Overview for Translin (TSN) (Middle Region) Peptide (ABIN5672045)
Target
Translin (TSN)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SRLSVNSVTA GDYSRPLHIS TFINELDSGF RLLNLKNDSL RKRYDGLKYD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TSN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Translin (TSN)
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Background
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This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
Alias Symbols: C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1
Protein Size: 228 -
Gene ID
- 7247
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NCBI Accession
- NM_001261401, NP_001248330
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UniProt
- Q15631
Target
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