Translin (TSN) (Middle Region) Peptide
TSN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Translin (TSN) products
- Translin (TSN)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LVTREAVTEI LGIEPDREKG FHLDVEDYLS GVLILASELS RLSVNSVTAG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TSN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Translin (TSN)
- Synonyms
- tsn Peptide, MGC52533 Peptide, TSN Peptide, CG11761 Peptide, Dmel\\CG11761 Peptide, TB-RBP Peptide, BCLF-1 Peptide, C3PO Peptide, RCHF1 Peptide, REHF-1 Peptide, TBRBP Peptide, TRSLN Peptide, 2610034C24Rik Peptide, AU040286 Peptide, translin L homeolog Peptide, translin Peptide, haloacid dehalogenase Peptide, Translin Peptide, tsn.L Peptide, TSN Peptide, trsn Peptide, MMAH_RS03470 Peptide, TAGG_RS05275 Peptide, Igag_0962 Peptide, MFER_RS03645 Peptide, DESMU_RS01315 Peptide, ARCVE_RS05265 Peptide, MZHIL_RS01310 Peptide, Tsn Peptide
- Background
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This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Alias Symbols: BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN
Protein Interaction Partner: HCVgp1,TSNAX,PPP1R15A,TSNAX,PPP1R15A,TSNAX
Protein Size: 228 - Molecular Weight
- 25 kDa
- Gene ID
- 7247
- NCBI Accession
- NM_004622, NP_004613
- UniProt
- Q15631
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