A Kinase (PRKA) Anchor Protein 8 (AKAP8) (Middle Region) Peptide
AKAP8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672053
Quick Overview for A Kinase (PRKA) Anchor Protein 8 (AKAP8) (Middle Region) Peptide (ABIN5672053)
Target
AKAP8
(A Kinase (PRKA) Anchor Protein 8 (AKAP8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KLARVDSEGD FSENDDAAGD FRSGDEEFKG EDELCDSGRQ RGEKEDEDED
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- AKAP8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))
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Background
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This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Alias Symbols: AKAP-8, AKAP95, AKAP 95, AKAP-95
Protein Size: 692 -
Gene ID
- 10270
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NCBI Accession
- NM_005858, NP_005849
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UniProt
- O43823
Target
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