Cadherin 8 (CDH8) (C-Term) Peptide
CDH8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Cadherin 8 (CDH8) products
- Cadherin 8 (CDH8)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QIYGYEGRGS VAGSLSSLES TTSDSDQNFD YLSDWGPRFK RLGELYSVGE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CDH8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Cadherin 8 (CDH8)
- Background
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This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Alias Symbols: Nbla04261
Protein Size: 799 - Gene ID
- 1006
- NCBI Accession
- NM_001796, NP_001787
- UniProt
- P55286
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