Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptide
EIF2C1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AGO1 (EIF2C1) products
- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RSVSIPAPAY YARLVAFRAR YHLVDKEHDS GEGSHISGQS NGRDPQALAK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- EIF2C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) peptide
EIF2C1 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
- Synonyms
- Ago Peptide, Ago-1 Peptide, Ago1 Peptide, CG6671 Peptide, Dm Ago1 Peptide, Dmel\\CG6671 Peptide, MRE20 Peptide, ago1 Peptide, ago1-1 Peptide, anon-WO0257455.29 Peptide, dAGO1 Peptide, dAgo1 Peptide, l(2)04845 Peptide, l(2)4845 Peptide, l(2)k00208 Peptide, l(2)k08121 Peptide, GB12654 Peptide, dsim_GLEANR_9718 Peptide, DsimGD25729 Peptide, GD25729 Peptide, EIF2C1 Peptide, EIF2C Peptide, GERP95 Peptide, Q99 Peptide, Eif2c1 Peptide, ARGONAUTE 1 Peptide, T1N15.2 Peptide, T1N15_2 Peptide, Argonaute-1 Peptide, protein argonaute-2 Peptide, argonaute 1 Peptide, Argonaute 1 Peptide, protein argonaute-1 Peptide, argonaute 1, RISC catalytic component Peptide, argonaute RISC catalytic subunit 1 Peptide, Stabilizer of iron transporter SufD / Polynucleotidyl transferase Peptide, AGO1 Peptide, LOC552062 Peptide, ago1 Peptide, LOC659936 Peptide, Dsim\AGO1 Peptide, Ago1 Peptide, LOC100386910 Peptide, LOC100482671 Peptide, LOC475337 Peptide
- Background
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This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Alias Symbols: Q99, EIF2C, hAgo1, EIF2C1, GERP95
Protein Size: 857 - Gene ID
- 26523
- NCBI Accession
- NM_012199, NP_036331
- UniProt
- Q9UL18
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