Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptide
EIF2C1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672141
$160.46
Plus shipping costs $50.00
100 μg
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Quick Overview for Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptide (ABIN5672141)
Target
AGO1 (EIF2C1)
(Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- RSVSIPAPAY YARLVAFRAR YHLVDKEHDS GEGSHISGQS NGRDPQALAK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- EIF2C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) peptide
EIF2C1 Reactivity: Human, Dog, Mouse, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))
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Background
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This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Alias Symbols: Q99, EIF2C, hAgo1, EIF2C1, GERP95
Protein Size: 857 -
Gene ID
- 26523
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NCBI Accession
- NM_012199, NP_036331
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UniProt
- Q9UL18
Target
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