Transmembrane Channel-Like 6 (TMC6) (N-Term) Peptide
TMC6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672191
Quick Overview for Transmembrane Channel-Like 6 (TMC6) (N-Term) Peptide (ABIN5672191)
Target
TMC6
(Transmembrane Channel-Like 6 (TMC6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- TLWRPEGTQS TATLRILASM PSRTIGRSRG AIISQYYNRT VQLRCRSSRP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TMC6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMC6 (Transmembrane Channel-Like 6 (TMC6))
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Background
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Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
Alias Symbols: EV1, EVER1, EVIN1, LAK-4P
Protein Size: 805 -
Gene ID
- 11322
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NCBI Accession
- NM_001127198, NP_001120670
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UniProt
- Q7Z403
Target
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