Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide
FRS2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672209
Quick Overview for Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Middle Region) Peptide (ABIN5672209)
Target
FRS2
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ANNTEWDTGY DSDERRDAPS VNKLVYENIN GLSIPSASGV RRGRLTSTST
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- FRS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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Background
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Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Alias Symbols: SNT, SNT1, FRS1A, FRS2A, SNT-1, FRS2alpha
Protein Size: 508 -
Gene ID
- 10818
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NCBI Accession
- NM_001042555, NP_001036020
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UniProt
- Q8WU20
Target
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