Runt-Related Transcription Factor 1 (RUNX1) (Middle Region) Peptide
RUNX1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RUNX1 products
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FTNPPQVATY HRAIKITVDG PREPRRHRQK LDDQTKPGSL SFSERLSELE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- RUNX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- Background
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha
Protein Size: 250 - Gene ID
- 861
- NCBI Accession
- NM_001001890, NP_001001890
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