Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Middle Region) Peptide
CAMK2A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672422
Quick Overview for Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Middle Region) Peptide (ABIN5672422)
Target
CAMK2A
(Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- NARRKLKGAI LTTMLATRNF SGGKSGGNKK SDGVKESSES TNTTIEDEDT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CAMK2A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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Background
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The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CAMKA
Protein Size: 478 -
Gene ID
- 815
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NCBI Accession
- NM_171825, NP_741960
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UniProt
- Q9UQM7
Target
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