P21-Activated Kinase 2 (PAK2) (Middle Region) Peptide
Quick Overview for P21-Activated Kinase 2 (PAK2) (Middle Region) Peptide (ABIN5672565)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- VLKFYDSNTV KQKYLSFTPP EKDGFPSGTP ALNAKGTEAP AVVTEEEDDD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PAK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PAK2 (P21-Activated Kinase 2 (PAK2))
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Background
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The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Alias Symbols: PAK65, PAKgamma
Protein Size: 524 -
Gene ID
- 5062
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NCBI Accession
- NM_002577, NP_002568
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UniProt
- Q13177
Target
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