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Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) Peptide

PI3K p85a Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672612

Quick Overview for Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) Peptide (ABIN5672612)

Target

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    QKGVRQKKLN EWLGNENTED QYSLVEDDED LPHHDEKTWN VGSSNRNKAE

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- PIK3R1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

    Background

    Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

    Alias Symbols: p85, AGM7, GRB1, IMD36, p85-ALPHA

    Protein Size: 361

    Gene ID

    5295

    NCBI Accession

    NM_001242466, NP_001229395
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