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Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptide

RGS14 Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN5672630

Quick Overview for Regulator of G-Protein Signaling 14 (RGS14) (C-Term) Peptide (ABIN5672630)

Target

RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

C-Term

Sequence

ELLNRVQSSG AHDQRGLLRK EDLVLPEFLQ LPAQGPSSEE TPPQTKSAAQ

Characteristics

This is a synthetic peptide designed for use in combination with anti- RGS14 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Regulator of G-Protein Signaling 14 (RGS14) peptide
RGS14 Host: Synthetic BP, Imm

Regulator of G-Protein Signaling 14 (RGS14) (C-Term) peptide
RGS14 Reactivity: Rat Host: Synthetic BP, WB

Regulator of G-Protein Signaling 14 (RGS14) (Middle Region) peptide
RGS14 Reactivity: Human, Mouse Host: Synthetic BP, WB

Regulator of G-Protein Signaling 14 (RGS14) peptide
RGS14 Reactivity: Human Host: Synthetic BP, BI

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Background

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Protein Size: 347

Gene ID

10636

NCBI Accession

NM_006480, NP_006471

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