Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptide
KCTD17
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all KCTD17 products
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SKELHSTPNG LSSESSRKTK STEEQLEEQQ QQEEEVEEVE VEQVQVEADA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- KCTD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
- Background
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Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. May be involved in endoplasmic reticulum calcium ion homeostasis.
Protein Size: 321 - Gene ID
- 79734
- NCBI Accession
- NM_001282684, NP_001269613
- UniProt
- Q8N5Z5
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