Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptide
KCTD17
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672785
Quick Overview for Potassium Channel Tetramerisation Domain Containing 17 (KCTD17) (Middle Region) Peptide (ABIN5672785)
Target
KCTD17
(Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DQAEFLCVVS KELHSTPNGL SSESSRKTKS TEEQLEEQQQ QEEEVEEVEV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- KCTD17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))
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Background
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Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation. May be involved in endoplasmic reticulum calcium ion homeostasis.
Protein Size: 321 -
Gene ID
- 79734
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NCBI Accession
- NM_001282684, NP_001269613
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UniProt
- Q8N5Z5
Target
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