14-3-3 theta (YWHAQ) (Middle Region) Peptide
YWHAQ
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672811
Quick Overview for 14-3-3 theta (YWHAQ) (Middle Region) Peptide (ABIN5672811)
Target
14-3-3 theta (YWHAQ)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- YWHAQ Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 14-3-3 theta (YWHAQ)
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Background
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This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Alias Symbols: 1C5, HS1, 14-3-3
Protein Size: 245 -
Gene ID
- 10971
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NCBI Accession
- NM_006826, NP_006817
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UniProt
- P27348
Target
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