Beclin 1, Autophagy Related (BECN1) (N-Term) Peptide
BECN1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672847
Quick Overview for Beclin 1, Autophagy Related (BECN1) (N-Term) Peptide (ABIN5672847)
Target
Beclin 1 (BECN1)
(Beclin 1, Autophagy Related (BECN1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- TTAQAKPGET QEEETNSGEE PFIETPRQDG VSRRFIPPAR MMSTESANSF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- BECN1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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Background
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This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Alias Symbols: ATG6, VPS30, beclin1
Protein Size: 450 -
Gene ID
- 8678
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NCBI Accession
- NM_001313998, NP_001300927
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UniProt
- Q14457
Target
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