Carbonic Anhydrase IX (CA9) (Middle Region) Peptide
CA9
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CA9 products
- CA9 (Carbonic Anhydrase IX (CA9))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KQLHTLSDTL WGPGDSRLQL NFRATQPLNG RVIEASFPAG VDSSPRAAEP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CA9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CA9 (Carbonic Anhydrase IX (CA9))
- Background
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Alias Symbols: MN, CAIX
Protein Size: 459 - Gene ID
- 768
- NCBI Accession
- NM_001216, NP_001207
- UniProt
- Q16790
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