Caldesmon 1 (CALD1) (C-Term) Peptide
CALD1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672861
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Caldesmon 1 (CALD1) (C-Term) Peptide (ABIN5672861)
Target
Caldesmon (CALD1)
(Caldesmon 1 (CALD1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ETAGLKVGVS SRINEWLTKT PDGNKSPAPK PSDLRPGDVS SKRNLWEKQS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CALD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Background
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This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CDM, HCAD, LCAD, H-CAD, L-CAD, NAG22
Protein Size: 532 -
Gene ID
- 800
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NCBI Accession
- NM_004342, NP_004333
Target
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