Baculoviral IAP Repeat Containing 3 (BIRC3) (N-Term) Peptide
Quick Overview for Baculoviral IAP Repeat Containing 3 (BIRC3) (N-Term) Peptide (ABIN5672885)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- RSLARAGFYY TGVNDKVKCF CCGLMLDNWK RGDSPTEKHK KLYPSCRFVQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- BIRC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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Background
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This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Alias Symbols: AIP1, API2, MIHC, CIAP2, HAIP1, HIAP1, MALT2, RNF49, c-IAP2
Protein Size: 604 -
Gene ID
- 330
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NCBI Accession
- NM_001165, NP_001156
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UniProt
- Q13489
Target
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