Chromosome 13 Open Reading Frame 18 (C13orf18) (Middle Region) Peptide
Quick Overview for Chromosome 13 Open Reading Frame 18 (C13orf18) (Middle Region) Peptide (ABIN5672972)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- DHPPCQLDIR LMRHKAVWIN PQDVQQQPQD LQSQVPAAGN SGTHFVTDAA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- C13ORF18 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- C13orf18 (Chromosome 13 Open Reading Frame 18 (C13orf18))
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Background
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This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
Alias Symbols: C13orf18
Protein Size: 527 -
Gene ID
- 80183
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NCBI Accession
- NM_001286761, NP_001273690
Target
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