Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (N-Term) Peptide
CASP4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5673017
Quick Overview for Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) (N-Term) Peptide (ABIN5673017)
Target
Caspase 4 (CASP4)
(Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- KKPLKVLESL GKDFLTGVLD NLVEQNVLNW KEEEKKKYYD AKTEDKVRVM
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- CASP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) peptide
CASP4 Reactivity: Human, Cow, Cat, Dog, Mouse Host: Synthetic BP, Imm
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
-
Background
-
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
Alias Symbols: TX, ICH-2, Mih1/TX, ICEREL-II, ICE(rel)II
Protein Size: 116 -
Gene ID
- 837
-
NCBI Accession
- NM_001225, NP_001216
Target
-
You are here:
