Charged Multivesicular Body Protein 5 (CHMP5) (Middle Region) Peptide
Quick Overview for Charged Multivesicular Body Protein 5 (CHMP5) (Middle Region) Peptide (ABIN5673033)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- APPPSLTDCI GTVDSRAESI DKKISRLDAE LVKYKDQIKK MREGPAKNMV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- CHMP5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
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Background
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CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
Alias Symbols: Vps60, CGI-34, PNAS-2, C9orf83, HSPC177, SNF7DC2
Protein Size: 171 -
Gene ID
- 51510
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NCBI Accession
- NM_001195536, NP_001182465
Target
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