Mastermind-Like 1 (MAML1) (N-Term) Peptide
Quick Overview for Mastermind-Like 1 (MAML1) (N-Term) Peptide (ABIN5673388)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- PATHLHDTVK RNLDSATSPQ NGDQQNGYGD LFPGHKKTRR EAPLGVAISS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAML1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MAML1 (Mastermind-Like 1 (MAML1))
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Background
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This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
Alias Symbols: Mam1, Mam-1
Protein Size: 1016 -
Gene ID
- 9794
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NCBI Accession
- NM_014757, NP_055572
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UniProt
- Q92585
Target
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