Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide
TBL1X
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TBL1X products
- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AAAAAAAATA AATAATTTSA GVSHQNPSKN REATVNGEEN RAHSVNNHAK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- TBL1X Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
- Background
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The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Alias Symbols: EBI, TBL1, SMAP55
Protein Size: 526 - Gene ID
- 6907
- NCBI Accession
- NM_001139466, NP_001132938
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