Corneodesmosin (CDSN) (C-Term) Peptide
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- Target See all Corneodesmosin (CDSN) products
- Corneodesmosin (CDSN)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LTLTGGPDGS PHPDPSAGAK PCGSSSAGKI PCRSIRDILA QVKPLGPQLA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CDSN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Corneodesmosin (CDSN)
- Background
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This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.
Alias Symbols: S, PSS, HTSS, PSS1, HTSS1, HYPT2
Protein Size: 529 - Gene ID
- 1041
- NCBI Accession
- NM_001264, NP_001255
- UniProt
- Q15517
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