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Coronavirus Spike Glycoprotein (CoV S) Peptide

CoV S Reactivity: Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2) Host: Synthetic InhA
Catalog No. ABIN6952488
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Quick Overview for Coronavirus Spike Glycoprotein (CoV S) Peptide (ABIN6952488)

Target

Coronavirus Spike Glycoprotein (CoV S)

Origin

Middle East Respiratory Syndrome Coronavirus (MERS-CoV), SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2)

Source

  • 1
Synthetic

Application

Inhibition Assay (InhA)
  • Sequence

    SLDQINVTFL DLEYEMKKLE EAIKKLEESY IDLKEL

    Characteristics

    EK1 / Pan-HCoV S Inhibitor

    Purity

    ≥ 95 %

    Components

    Each vial contains 100 μg of NET peptide.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Powder

    Storage

    RT,4 °C,-20 °C

    Storage Comment

    Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Xia, Zhu, Liu, Lan, Xu, Wu, Ying, Liu, Shi, Jiang, Lu: "Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein." in: Cellular & molecular immunology, (2020) (PubMed).

    Lu: "Drug treatment options for the 2019-new coronavirus (2019-nCoV)." in: Bioscience trends, Vol. 14, Issue 1, pp. 69-71, (2020) (PubMed).

    Xia, Yan, Xu, Agrawal, Algaissi, Tseng, Wang, Du, Tan, Wilson, Jiang, Yang, Lu: "A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike." in: Science advances, Vol. 5, Issue 4, pp. eaav4580, (2019) (PubMed).

  • Target

    Coronavirus Spike Glycoprotein (CoV S)

    Target Type

    Viral Protein

    Molecular Weight

    4332
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