Hepatitis C Virus NS3 (HCV NS3) (AA 1192-1459) Peptide
HCV NS3
Reactivity: Hepatitis C Virus (HCV)
Host: Escherichia coli (E. coli)
ELISA, WB
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- Target See all HCV NS3 products
- HCV NS3 (Hepatitis C Virus NS3 (HCV NS3))
- Peptide Type
- Recombinant
- Protein Region
- AA 1192-1459
- Origin
- Hepatitis C Virus (HCV)
- Source
- Escherichia coli (E. coli)
- Application
- ELISA, Western Blotting (WB)
- Characteristics
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Purified recombinant Hepatitis C Virus NS3 protein
Expression System: E.coli - Purification
- Proprietary chromatographic technique
- Purity
- > 90 % pure
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Buffer
- 20 mM Tris-HCl, pH 8.0, with 20 mM beta mercaptoethanol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- HCV NS3 (Hepatitis C Virus NS3 (HCV NS3))
- Target Type
- Viral Protein
- Background
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HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Alternative Names: HCV NS3 protein, HCV protein, Hep C protein, Hepatitis C protein, HCV Recombinant protein, HCV NS3 Genotype-1a protein, HCV NS3 Genotype 1a protein
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