Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-141) Peptide
CSF2
Reactivity: Mouse
Host: Escherichia coli (E. coli)
SDS
1 image
Catalog No. ABIN934959
Quick Overview for Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-141) Peptide (ABIN934959)
Target
GM-CSF (CSF2)
(Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
Origin
Mouse
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
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Peptide Type
- Recombinant
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Protein Region
- AA 18-141
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Sequence
- MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
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Characteristics
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Purified recombinant Mouse GM-CSF protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. -
Purity
- > 95 % pure
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Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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Application Notes
- GM-CSF protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Background
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GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. Mouse GM-CSF protein is 125 amino acids and shares approximately 60 % homology with the human GM-CSF protein. Recombinant mouse GM-CSF was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: Granulocyte-macrophage colony stimulating factor 2 protein, MGI-IGM protein, mGM-CSF protein, Granulocyte-macrophage colony stimulating factor 2, Csfgm protein, Csf2 protein -
Molecular Weight
- 14 kDa (125 AA)
Target
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