Transthyretin (TTR) (AA 21-147) Peptide
TTR
Reactivity: Human
Host: Escherichia coli (E. coli)
SDS
1 image
Catalog No. ABIN935081
Quick Overview for Transthyretin (TTR) (AA 21-147) Peptide (ABIN935081)
Target
TTR
(Transthyretin (TTR))
Origin
Human
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
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Peptide Type
- Recombinant
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Protein Region
- AA 21-147
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Sequence
- MGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHE HAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE
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Characteristics
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Purified recombinant Human Prealbumin protein
Expression System: E.coli -
Purity
- > 95 % pure
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Application Notes
- Prealbumin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- TTR (Transthyretin (TTR))
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Background
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Prealbumin, also known as Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). Recombinant human Prealbumin was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Amyloidosis I protein, TBPA protein, HsT2651 protein, Transthyretin protein, Prealbumin amyloidosis type I protein, Amyloid polyneuropathy protein, Senile systemic amyloidosis protein, ATTR protein, Dysprealbuminemic euthyroidal hyperthyroxinemia protein, TTR protein, PALB protein, Dystransthyretinemic hyperthyroxinemia protein, TTR protein. -
Molecular Weight
- 13.8 kDa (128 AA)
Target
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