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Nucleocapsid (Core) (AA 2-192) Peptide

Reactivity: Hepatitis C Virus (HCV) Host: Escherichia coli (E. coli) ELISA, WB
Catalog No. ABIN5676021

Quick Overview for Nucleocapsid (Core) (AA 2-192) Peptide (ABIN5676021)

Target

Nucleocapsid (Core)

Origin

Hepatitis C Virus (HCV)

Source

Escherichia coli (E. coli)

Application

ELISA, Western Blotting (WB)
  • Peptide Type

    Recombinant

    Protein Region

    AA 2-192

    Characteristics

    Hepatitis C Virus Core 22 kDa recombinant protein
    Expression System: E.coli

    Purification

    Proprietary chromatographic technique

    Purity

    > 95 % pure
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    25 mM tris-HCl, pH-8, with 1.5 M urea, 0.2 % Triton-X and 52 % glycerol.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C
  • Target

    Nucleocapsid (Core)

    Target Type

    Viral Protein

    Background

    HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
    Alternative Names: HCV Recombinant protein, Hepatitis C protein, Hep C protein, HCV protein, HVC Nucleocapsid (Core) 22 kDa protein

    Molecular Weight

    22 kDa
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