Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) Peptide
UCP2
Reactivity: Mouse
Host: Synthetic
BP, ELISA
Sodium azide
Catalog No. ABIN935879
Quick Overview for Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) Peptide (ABIN935879)
Target
UCP2
(Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), ELISA
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Peptide Type
- Synthetic
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Cross-Reactivity (Details)
- This Mouse UCP2 peptide sequences is 92 % conserved in rat and hamster, 86 % in human, canine, and pig UCP2. It has no significant homology with UCP1, UCP3-5.
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Characteristics
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A synthetic UCP2 Blocking peptide for use as a blocking control in assays to test for specificity of UCP2 antibody,
Alternative Names: UCP-2 Blocking peptide, UCP 2 Blocking peptide, Uncoupling Protein 2 Blocking peptide, UCP2 Control peptide, UCP2, UCP-2, UCP 2, UCP-2 Blocking Peptide, UCP 2 Blocking Peptide
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Application Notes
- ELISA: 50-100 ng/well
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Assay Procedure
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UCP2 Blocking peptide, catalog no. ABIN935879 is also available for use as a blocking control in assays to test for the specificity of this UCP2 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in 100 µL of water, do not dilute further until ready to use.
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Buffer
- Lyophilized from PBS, pH 7.5, with 0.05 % NaN3.
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Preservative
- Sodium azide
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Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
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Background
- Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. UCP3 is predicted to contain 6 transmembrane domains. The UCP3S lacks the 6th transmembrane domain and it is only 275 AA long. Mouse/rat UCP2 is A 309 AA (human 309 AA chromosome 7, ~95 % homology) mitochondrial uncoupling protein. UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation.
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Molecular Weight
- <3 kDa
Target
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