Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (Middle Region) Peptide
UCP2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UCP2 products
- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- STTGALAVAV AQPTDVVKVR FQAQARAGGG RRYQSTVNAY KTIAREEGFR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- UCP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
- Synonyms
- UCP2 Peptide, DKFZp470P1633 Peptide, ucp2 Peptide, MGC53319 Peptide, MGC75881 Peptide, cb74 Peptide, ATUCP2 Peptide, K19M22.21 Peptide, K19M22_21 Peptide, uncoupling protein 2 Peptide, BMIQ4 Peptide, SLC25A8 Peptide, UCPH Peptide, Slc25a8 Peptide, mitochondrial uncoupling protein 2 Peptide, uncoupling protein 2 Peptide, uncoupling protein 2 (mitochondrial, proton carrier) L homeolog Peptide, uncoupling protein 2 (mitochondrial, proton carrier) Peptide, uncoupling protein 1 Peptide, PTRG_09289 Peptide, UCP2 Peptide, LOC100282746 Peptide, ucp2.L Peptide, ucp2 Peptide, ucp1 Peptide, Ucp2 Peptide
- Background
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Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.
Alias Symbols: UCPH, BMIQ4, SLC25A8
Protein Size: 309 - Gene ID
- 7351
- NCBI Accession
- NM_003355, NP_003346
- UniProt
- P55851
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