Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1) Peptide
LDLRAP1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all LDLRAP1 products
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- WTDTRETLLE GMLFSLKYLG MTLVEQPKGE ELSAAAIKRI VATAKASGKK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of LDLRAP1 antibody,
Alternative Names: LDLRAP1 control peptide, LDLRAP1 antibody Blocking Peptide, Anti-LDLRAP1 Blocking Peptide, Low Density Lipoprotein Receptor Adaptor Protein 1 Blocking Peptide, ARH Blocking Peptide, ARH1 Blocking Peptide, ARH2 Blocking Peptide, DKFZp586D0624 Blocking Peptide, FHCB1 Blocking Peptide, FHCB2 Blocking Peptide, MGC34705 Blocking Peptide, LDLRAP1, LDLRAP-1, LDLRAP 1, LDLRAP-1 Blocking Peptide, LDLRAP 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1 (LDLRAP1))
- Background
- LDLRAP1 is an adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). LDLRAP1 may be required for LDL binding and internalization but not for receptor clustering in coated pits. LDLRAP1 may facilitate the endocytocis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits.
- Molecular Weight
- 34 kDa
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